α,α,α,6-Tetrafluoro-m-toluoyl chloride

α,α,α,6-Tetrafluoro-m-toluoyl chloride - Names and Identifiers

Name	2-fluoro-5-(trifluoromethyl)benzoyl chloride
Synonyms	à,à,à,6-tetrafluoro-m-toluoyl chloride α,α,α,6-Tetrafluoro-m-toluoyl chloride 2-fluoro-5-(trifluoromethyl)benzoyl chloride 2-FLUORO-5-(TRIFLUOROMETHYL)BENZOYL CHLORIDE alpha,alpha,alpha,6-Tetrafluoro-m-toluoyl chloride
CAS	207981-46-2
EINECS	632-656-4
InChI	InChI=1/C8H3ClF4O/c9-7(14)5-3-4(8(11,12)13)1-2-6(5)10/h1-3H

α,α,α,6-Tetrafluoro-m-toluoyl chloride - Physico-chemical Properties

Molecular Formula	C8H3ClF4O
Molar Mass	226.56
Density	1.499 g/mL at 25 °C (lit.)
Boling Point	191 °C (lit.)
Flash Point	200°F
Vapor Presure	0.521mmHg at 25°C
Specific Gravity	1.499
Storage Condition	Refrigerator (+4°C)
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.468(lit.)
MDL	MFCD00061156

α,α,α,6-Tetrafluoro-m-toluoyl chloride - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3265 8/PG 2
WGK Germany	3
HS Code	29163990
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

α,α,α,6-Tetrafluoro-m-toluoyl chloride - Introduction

2-fluoro-5-(trifluoromethyl)benzoyl chloride is an organic compound with the chemical formula C8H4ClF4O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid
-Boiling point: 96-98 ° C
-Relative density: 1.476
-Melting point:-54 ° C

Use:
2-fluoro-5-(trifluoromethyl)benzoyl chloride is commonly used in the field of organic synthesis and pharmaceutical chemistry, and has certain important applications.
-It can be used as a raw material for the preparation of organic compounds such as pesticides, fungicides, and pharmaceutical intermediates.
-In drug research, it is used to synthesize fluorine-containing CYP1A1 inhibitors.
-In addition, it can also be used to kill microorganisms and prepare preservatives.

Method:
2-fluoro-5-(trifluoromethyl)benzoyl chloride can be prepared in many ways. The following is a common method:
-Using 2-fluoro -5-(trifluoromethyl) benzoic acid as raw material, it is prepared by acyl chloride reaction.

Safety Information:
- 2-fluoro-5-(trifluoromethyl)benzoyl chloride is an irritating compound and should be avoided from skin contact and inhalation.
-When using, wear appropriate personal protective equipment, such as chemical protective gloves and respiratory protection.
-During storage and handling, avoid contact with oxidants and combustibles to prevent fire.
-If swallowed or unwell, seek medical attention immediately.

Last Update：2024-04-09 02:00:44